N'afọ ndị 1990, ndị ọkachamara ahụike Switzerland chọpụtara na platelet nwere ike ịmepụta ọnụ ọgụgụ buru ibu nke ihe na-eto eto na nnukwu mkpokọta, nke nwere ike imezi ọnyá anụ ahụ ngwa ngwa na nke ọma.E mesịa, a na-etinye PRP n'ọrụ ịwa ahụ dị iche iche dị n'ime na nke mpụga, ịwa ahụ plastik, ntụgharị akpụkpọ anụ, wdg.
Anyị na mbụ webatara ngwa nke PRP (Platelets Rich Plasma) na ntụgharị ntutu iji nyere aka mgbake ọnya na uto ntutu;N'ezie, nnwale ọzọ ị ga-anwale bụ ịbawanye mkpuchi nke isi ntutu isi site na ịgbanye PRP.Ka anyị hụ ihe a ga-esi na ya pụta site n'ịgbanye plasma autologous platelet enriched na ihe uto dị iche iche n'ime ndị nwoke nwere alopecia, nke bụkwa ọgwụgwọ anyị nwere ike ịtụ anya iji lụso ntutu ọgụ.
Tupu na n'oge usoro nhazi ntutu dum, ndị ọrịa na-agwọ ọrịa na PRP na ndị na-adịghị etinye ya na PRP nwere ike ime ka ntutu na-eto ngwa ngwa.N'otu oge ahụ, onye edemede ahụ tụkwara atụmatụ nyocha iji gosi ma plasma bara ụba nke platelet nwere otu mmetụta ahụ n'ịkwalite ntutu dị mma.Kedu ụdị ọnya ekwesịrị iji yana ole ihe na-eto eto kwesịrị ịgbanye ozugbo ka ọ dị irè?PRP nwere ike gbanwee ntutu isi nke nwayọọ nwayọọ na androgenic alopecia, ma ọ bụ ọ nwere ike ịkpalite ntutu isi nke ọma iji melite androgenic alopecia ma ọ bụ ọrịa ntutu isi ndị ọzọ?
N'ime obere nnwale nke ọnwa asatọ a, a gbanyere PRP n'ime akpụkpọ anụ nke androgenic alopecia na alopecia.E jiri ya tụnyere ndị na-ahụ maka njikwa, ọ nwere ike gbanwee ntutu isi nke nwayọọ nwayọọ;Tụkwasị na nke ahụ, mgbe a na-agbanye n'ime ndị ọrịa nwere isi nkwọcha, enwere ike ịhụ uto ntutu ọhụrụ otu ọnwa ka e mesịrị, mmetụta ya nwere ike ịdịru ihe karịrị ọnwa asatọ.
Okwu mmalite
N'afọ 2004, mgbe otu n'ime ndị nchọpụta mesoro ọnyá ịnyịnya na PRP, ọnya ahụ gwọrọ n'ime otu ọnwa na ntutu na-eto, mgbe ahụ, a na-etinye PRP na ịwa ahụ ntutu isi;Ndị nchọpụta ahụ gbalịkwara ịgbanye PRP n'isi ụfọdụ ndị ọrịa tupu a na-atụgharị ntutu isi, wee chọpụta na ntutu nke ndị ọrịa ahụ yiri ka ọ na-arị elu (1).Ndị nchọpụta ahụ kwenyere na ịghaghachi azụ na mmetụta nke ọdịnaya dị elu nke ihe na-eto eto nwere ike ime ka mkpụrụ ndụ follicle na-eto eto na ntutu isi nke ebe anaghị arụ ọrụ.A na-edozi ọbara ahụ nke ọma.A na-ekewapụta platelet na protein ndị ọzọ na plasma ma nwee nnukwu mkpokọta platelet.Iji ruo ọkọlọtọ nke mmetụta ọgwụgwọ, site na 1 microliter (0.000001 liter) nwere 150000-450000 platelet ruo 1 microliter (0.000001 liter) nwere 1000000 platelet (2).
Platelet α nwere ụdị ihe uto asaa na granules, gụnyere ihe na-eto eto epithelial, ihe na-eto eto fibroblast, ihe na-eto eto thrombogen na ihe na-agbanwe uto β, na-agbanwe ihe uto α, Interleukin-1, na vascular endothelial growth factor (VEGF).Na mgbakwunye, a na-agbakwunye peptides antimicrobial, catecholamines, serotonin, Osteonectin, von Willebrand factor, proaccelenn na ihe ndị ọzọ.Oke ahụ nwere ihe karịrị 100 ụdị ihe uto, nke nwere ike ime ọnya.Na mgbakwunye na ihe ndị na-eto eto, plasma dịpụrụ adịpụ nke platelet sparse (PPP) nwere mkpụrụ ndụ adhesion cell atọ (CAM), Fibrin, fibronectin, na vitronectin, protein multifunctional nke na-edozi isi ihe na alaka iji chịkwaa uto cell, adhesion, proliferation. dị iche iche na mmeghari ohuru.
Takakura, et al.kwuru na mgbaàmà PDCF (platelet derived growth factor) metụtara mmekọrịta nke ntutu isi epidermal na dermal stromal cell, na ọ dị mkpa maka ịmepụta eriri ntutu (3).Na 2001, Yano et al.rụtụrụ aka na VFLGF na-achịkwa usoro nke ntutu isi na-eto eto, na-enye ihe akaebe na-egosi na ịba ụba vaskụla vaskụla ntutu isi nwere ike ịkwalite uto ntutu ma mee ka ntutu isi na nha ntutu (4).
PS: Ihe na-akpata uto nke Platelet, PDCF.Ihe mbụ na-eto eto nke US FDA kwadoro iji gwọọ mmerụ anụ ahụ na-adịghị ala ala bụ ihe mbụ na-eto eto na-ewepụta site na mkpali mgbe mmerụ ahụ gasịrị.
PS: Ihe na-eto eto vaskụla endothelial, VEGF.Ọ bụ otu n'ime ihe nchịkwa kachasị mkpa na-achịkwa mgbasa nke sel endothelial, angiogenesis, vasculogenesis na vaskụla permeability.
Ọ bụrụ na anyị kwenyere na mgbe ntutu isi agbadala ruo n'ókè anyị na-apụghị iji anya gba ọtọ hụ uto ntutu, a ka nwere ohere maka ntutu isi na-eto eto (5).Tụkwasị na nke ahụ, ọ bụrụ na ntutu isi nke ntutu dị mma dị ka nke ntutu isi na-adịghị ahụkebe, e nwere sel stem zuru ezu na epidermis na mpụta (6), ọ ga-ekwe omume ime ka ntutu dị gịrịgịrị ma na-arị elu n'isi nkwọcha nwoke.
Oge nzipu: Dec-20-2022